Xyoo 1968, Kruger-Theimer tau piav qhia yuav ua li cas cov qauv tshuaj pharmacokinetic tuaj yeem siv los tsim cov tshuaj noj kom zoo. Qhov no Bolus, tshem tawm, Hloov pauv (BET) kev tswj hwm muaj xws li:
ib koob tshuaj bolus suav los sau rau hauv nruab nrab (ntshav) compartment,
ib qho infusion tsis tu ncua sib npaug ntawm kev tshem tawm tus nqi,
ib qho infusion uas them rau kev hloov mus rau cov ntaub so ntswg peripheral: [exponentially txo tus nqi]
Kev coj ua ib txwm muaj suav nrog kev suav cov tshuaj infusion rau propofol los ntawm Roberts txoj kev. Ib koob tshuaj 1.5 mg / kg loading yog ua raws li kev txhaj tshuaj ntawm 10 mg / kg / teev uas txo qis rau 8 thiab 6 mg / kg / teev ntawm kaum feeb ib ntus.
Kev cuam tshuam qhov chaw phiaj xwm
Cov teebmeem tseem ceeb ntawmtshuaj loogintravenous agents yog cov sedative thiab hypnotic teebmeem thiab qhov chaw uas cov tshuaj exerts cov teebmeem, hu ua qhov chaw nyhuv yog lub hlwb. Hmoov tsis zoo nws tsis muaj peev xwm ua tau hauv kev kho mob los ntsuas lub paj hlwb [qhov chaw cuam tshuam]. Txawm hais tias peb tuaj yeem ntsuas lub hlwb ncaj qha, nws yuav tsum paub qhov tseeb hauv cheeb tsam cov ntsiab lus lossis txawm tias cov receptor concentrations qhov twg cov tshuaj siv nws cov txiaj ntsig.
Ua tiav qhov tsis tu ncua propofol concentration
Daim duab hauv qab no qhia txog tus nqi infusion xav tau ntawm tus nqi txo qis tom qab txhaj tshuaj bolus txhawm rau txhawm rau tswj lub xeev cov ntshav concentration ntawm propofol. Nws kuj qhia tau hais tias lub lag luam ntawm cov ntshav thiab cov nyhuv ntawm qhov chaw concentration.
Post lub sij hawm: Nov-05-2024